Now showing items 1-6 of 6
ELUCIDATING THE FUNCTION AND DYNAMICS OF RESIDENT AND RECRUITED MACROPHAGE POPULATIONS IN THE LUNG
(Johns Hopkins University, 2014-07-30)
Acute lung injury and chronic lung inflammation are major causes of morbidity and mortality in the US and worldwide. The cellular and molecular factors that function to limit the extent of acute and chronic inflammation ...
Discovery and validation of inhibitors targeting protein-protein interactions in the plasmodial glideosome
(Johns Hopkins University, 2015-07-01)
Plasmodium falciparum is the parasite responsible for the most deadly cases of malaria in humans. Emerging resistance of P. falciparum to available treatments is of concern, and necessitates the development of novel compounds ...
The effects of genetic modification on Anopheles stephensi
(Johns Hopkins University, 2015-01-17)
Various species of mosquitoes from the genus Anopheles vector the Plasmodium spp. parasites responsible for human malaria. While traditional, drug and insecticide based, efforts to control malaria have met with some success ...
TRANSGENIC RODENT MALARIA PARASITES FOR THE EVALUATION OF PROTECTIVE IMMUNITY AGAINST PLASMODIUM FALCIPARUM
(Johns Hopkins University, 2015-08-27)
Malaria is a global health emergency. Current estimates indicate that 3.3 billion people live at risk of infection and that more than half a million lives are lost to the disease annually, most of them from children under ...
FATTY ACID METABOLISM IN APICOMPLEXAN PARASITES
Plasmodium falciparum and Toxoplasma gondii are human parasites that belong to the phylum Apicomplexa and are the causative agents of malaria and toxoplasmosis, respectively. These parasites infect billions of people ...
Measuring Child Health Coverage: Validation of Maternal-Reported Care-seeking and New Methods for Estimating Coverage of Appropriate Management of Childhood Illness
(Johns Hopkins University, 2017-03-27)
Problem Statement: Accurate data on coverage of health interventions is required for continued reduction in child mortality. This study assessed the validity of the standard indicator on care-seeking for child illness and ...