ETD -- Graduate theses
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For information about submitting electronic theses and dissertations, please see the ETD information page
Recent Submissions
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In Vitro Reconstitution of Argonaute poly(ADP-ribosyl)ation and Its Impact on microRNA Activity
(Johns Hopkins UniversityUSA, 2013-11-08)MicroRNA-mediated gene regulation is an important component of cell biology, involved in nearly all cellular processes. MicroRNAs are ~22 nucleotide non-coding RNAs that recognize complimentary mRNA targets and prevent ... -
Development of a Conformal Textile Electrode Liner for the Purpose of Myoelectric Prosthesis Control
(Johns Hopkins UniversityUSA, 2013-10-09)In upper-extremity myoelectric prostheses, hard surface electromyography (sEMG) electrodes are typically placed in a rigid or semi-rigid socket worn over the residual limb. The resulting interface does not offer optimal ... -
THE IMMUNOLOGICAL EFFECTS OF CHECKPOINT BLOCKADE IN COMBINATION WITH A TYROSINE KINASE INHIBITOR IN A MURINE MODEL OF RENAL CELL CARCINOMA
(Johns Hopkins UniversityUSA, 2015-08-24)Renal Cell Carcinoma (RCC) is responsible for approximately 13,500 deaths in the US each year and 65,000 new cases are diagnosed here annually. Despite the approval of multiple new drugs targeting mTOR and angiogenic ... -
BIODEGRADATION OF CHLOROBENZENES UNDER AEROBIC AND ANAEROBIC CONDITIONS
(Johns Hopkins UniversityUSA, 2016-12-20)Bioremediation is a process that leverages the unique metabolisms of microorganisms in order to treat harmful contaminants that have entered the environment. This project explores the use of both aerobic and anaerobic ... -
The Role of Social Media in Cancer Recovery
(Johns Hopkins UniversityUSA, 2016-12-13)This study investigates the role of social media during cancer treatment and recovery. Qualitative research methods were used, which included semi-structured, in-depth interviews with 20 cancer survivors. Findings indicate ... -
IMPLEMENTATION OF NATIONAL SCIENCE FOUNDATION BROADER IMPACTS CRITERION FROM 1997-2017
(Johns Hopkins UniversityUSA, 2017-12-19)Broader Impacts -
BOTSWANA HAS A MORAL DUTY TO EXPAND ACCESS TO ANTIRETROVIRAL THERAPY TO SURVIVAL MIGRANTS
(Johns Hopkins UniversityUSA, 2017-12-18)Social, political and economic problems since Zimbabwe’s post-independence period have resulted in the creation of survival migrants that flock to neighboring countries for a better life. In the same period, HIV/AIDS had ... -
Genetic Testing Preferences and Intentions in Patients with Clinically Diagnosed Familial Hypercholesterolemia
(Johns Hopkins UniversityUSA, 2017-12-18)Purpose Familial Hypercholesterolemia (FH) is a common (1/250) Mendelian disorders that results in elevated LDL cholesterol levels from birth, and if left untreated can result in premature heart disease. Only up to 10% of ... -
We Can Do It: Achieving Equal Representation of Gender in the United States Congress
(Johns Hopkins UniversityUSA, 2017-12-19)One hundred years after the ratification of the 19th Amendment, women remain significantly under-represented in the federal legislature, occupying only 19.6 percent of congressional seats in 2017. Holding fewer than half ... -
Radio-morphology: Parametric Shape-Based Features in Radiotherapy
(Johns Hopkins UniversityUSA, 2017-12-18)In radiotherapy, it is necessary to characterize dose over the patient anatomy to target areas and organs at risk. Current tools provide methods to describe dose in terms of percentage of volume and magnitude of dose, but ... -
Improving Antibody CDR Template Selection by Structural Cluster Prediction
(Johns Hopkins UniversityUSA, 2017-12-28)With the advent of high-throughput sequencing, antibody sequences can be acquired at much greater speed than corresponding structures, creating a need for rapid structure determination. Computational modeling is the only ... -
The Design, Experimentation, and Characterization of a High-Pressure Round-Edged Orifice Plate Test Facility
(Johns Hopkins UniversityUSA, 2017-12-15)Orifice plates are commonly found in fluid measurement devices, piping systems, and engines. They are used as flow measurement devices, appear as restrictors in piping, or are used as fuel injectors inside internal ... -
Test Drive Online Education: How a Simulated Online Learning Experience Influences Prospective Student Perceptions, Attitudes, and Behaviors
(Johns Hopkins UniversityUSA, 2017-12-18)The online education marketplace for higher education has become increasing saturated with competition since the advent of the World Wide Web. Academic institutions have had to find innovative ways to attract new online ... -
Propensity Scoring for Comparison of Wound Care Treatments: A Case Study
(Johns Hopkins UniversityUSA, 2017-12-13)Treatment effect modeling in an observational study is challenging. In an observational study, participants' conditions in diverse treatment groups may differ from each other to a large extent, which can result in potential ... -
Variability in the Experimental Response of Thermally Excited Aluminum Alloys
(Johns Hopkins UniversityUSA, 2017-12-13)The use of aluminum alloys for load bearing elements continues to expand rapidly across the marine, aviation, and commercial building industries, among others. Some factors driving this expansion are aluminum's low density, ... -
Lab-Based Filtration System Improving Recovery and Reducing Time to Detection for Diagnosis of Sepsis
(Johns Hopkins UniversityUSA, 2017-12-12)Rapid and accurate detection of a blood stream infection is critical for the proper management of patients displaying symptoms of sepsis. Current blood culture systems are both time consuming and may yield low recovery in ... -
DETERMINISTIC CONSTRUCTION OF SYNCHRONIZATION STRING OVER SMALL ALPHABET
(Johns Hopkins UniversityUSA, 2017-12-07)Synchronization string, first introduced by Haeupler and Shahrasbi [10], is a strong tool in construction of error correcting codes for in- sertion and deletion errors (insdel codes). Synchronization string pro- vides a ... -
Questioning the Normative: On Deconstruction as Value Theory
(Johns Hopkins UniversityUSA, 2017-11-15)My thesis explores Derrida's political thought, with special focus on his essay "Force of Law: the Mystical Foundation of Authority". My main argument is that for Derrida, justice does not have its normative structure, or ... -
SPATIAL-TEMPORAL VARIATIONS AND RISK DETERMINANTS OF VIBRIO PARAHAEMOLYTICUS INFECTIONS IN WASHINGTON STATE
(Johns Hopkins UniversityUSA, 2017-12-11)Vibrio parahaemolyticus is a naturally-occurring halophilic and asporogenous gram-negative bacterium widely distributed in marine environments and frequently detected in shellfish, particularly oysters. V. parahaemolyticus ... -
Stability of Self-Assembling Drug Amphiphiles in Biological Environments
(Johns Hopkins UniversityUSA, 2017-10-18)The search of understanding the interaction of self-assembling nanostructures with proteins in biological environments is leading to the rapid development of key applications, including improved drug delivery systems with ...
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