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Mouse PVRIG Has CD8+ T Cell–Specific Coinhibitory Functions and Dampens Antitumor Immunity
A limitation to antitumor immunity is the dysfunction of T cells in the tumor microenvironment, in part due to upregulation of coinhibitory receptors such as PD-1. Here, we describe that poliovirus receptor-related ... -
Trump or Bust: How Political Identification Impacts Opinions on Health Reform
(2022-05)Considerable research has been conducted on the development of one’s political ideology and its impact on opinions regarding policy. This study contributes to this body of research by studying factors which influence the ... -
Introspections: Medical Stories and Other Essays
(2022-05)This collection of stories is about discovering identity, and the dreams that were born from this long hunt. Such a pursuit might have been chasing an ideal that never truly existed. Or worse yet, chasing somebody else’s ... -
Professionals Who Care: A Nonprofit Design for Inclusivity of Caregivers in the Workplace
(2022-05)Informal caregivers provide essential care to the disabled, ill, aging, or injured, services that are valued over $470 billion annually in the United States. Research has shown that nearly half of these caregivers had no ... -
Establishing a Government Run Safe Injection Facility in the City of Philadelphia
(2022-05)The City of Philadelphia is currently facing an opioid epidemic of unprecedented proportions, with 1,214 drug related overdoses in 2020 alone. The problem has been so detrimental that in 2019, the city had the highest rate ...